Arrowsmith by Sinclair Lewis (1925)

Martin Arrowsmith, an idealistic young doctor, battles against commercial medicine, institutional politics, and his own ambition to pursue pure scientific research. Lewis' most sympathetic novel and his tribute to the scientific spirit.

Historical Significance:
Published in 1925, Arrowsmith was awarded the Pulitzer Prize for Fiction — which Lewis famously declined, saying the prize was awarded not for the best novel but for the one that "best presents the...

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