Methamphetamine (METH) abuse has become a major public health problem world-wide, as demonstrated by increases in the number of emergency room visits, substance abuse treatment episodes, and arrests attributable to METH manufacture and abuse. However, there are currently no pharmacological treatments for the wide range of symptoms associated with METH abuse. One of the reasons for this problem is that our knowledge of the cellular and molecular mechanisms underlying the development of METH-induc...